Leukotriene Antagonists as First-Line or Add-on Asthma-Controller Therapy

Study results at 2 months suggest that LTRA was equivalent to an inhaled glucocorticoid as first-line controller therapy and to LABA as add-on therapy for diverse primary care patients. Equivalence was not proved at 2 years.

N Engl J Med 2011; 364:1695-1707